As at December 31, 2022 Equity (100% owned unless otherwise noted in brackets beside company name) Interest Address Description Manulife (Cambodia) PLC Phnom Penh, Cambodia Life insurance company Manulife Myanmar Life Insurance Company Limited Yangon, Myanmar Life insurance company Manufacturers Life Reinsurance Limited St. Michael, Barbados Provides life and annuity reinsurance to affiliates Manulife (Vietnam) Limited Ho Chi Minh City, Vietnam Life insurance company Manulife Investment Fund Management (Vietnam) Ho Chi Minh City, Vietnam Fund management company Company Limited Manulife International Holdings Limited Hong Kong, China Holding company Manulife (International) Limited Hong Kong, China Life insurance company Manulife-Sinochem Life Insurance Co. Ltd. (51%) Shanghai, China Life insurance company Manulife Investment Management International Hong Kong, China Holding company Holdings Limited Manulife Investment Management (Hong Kong) Hong Kong, China Investment management and advisory company Limited marketing mutual funds Manulife Investment Management (Taiwan) Taipei, Taiwan (China) Investment management company Co., Ltd. Manulife Life Insurance Company (Japan) Tokyo, Japan Life insurance company Manulife Investment Management (Japan) Limited Tokyo, Japan Investment management and advisory company and mutual fund business Manulife Holdings Berhad (61.6%) Kuala Lumpur, Malaysia Holding company Manulife Insurance Berhad (61.6%) Kuala Lumpur, Malaysia Life insurance company Manulife Investment Management (Malaysia) Berhad Kuala Lumpur, Malaysia Asset management company (61.6%) Manulife (Singapore) Pte. Ltd. Singapore Life insurance company Manulife Investment Management (Singapore) Pte. Ltd. Singapore Asset management company The Manufacturers Life Insurance Co. (Phils.), Inc. Makati City, Philippines Life insurance company Manulife Chinabank Life Assurance Corporation Makati City, Philippines Life insurance company (60%) PT Asuransi Jiwa Manulife Indonesia Jakarta, Indonesia Life insurance company PT Manulife Aset Manajemen Indonesia Jakarta, Indonesia Investment management and investment advisor Manulife TEDA Fund Management Co., Ltd Beijing, China Mutual fund company in China Manulife Investment Management (Europe) Limited $ 34 London, England Investment management company for Manulife Financial’s international funds Manulife Assurance Company of Canada $ 64 Toronto, Canada Life insurance company EIS Services (Bermuda) Limited $ 902 Hamilton, Bermuda Investment holding company Berkshire Insurance Services Inc. $ 1,868 Toronto, Canada Investment holding company JH Investments (Delaware) LLC Boston, U.S.A. Investment holding company Manulife Securities Incorporated $ 151 Oakville, Canada Investment dealer Manulife Investment Management (North America) Limited $ 4 Toronto, Canada Investment advisor 214 | 2022AnnualReport | NotestoConsolidatedFinancialStatements